Renal and neurological side effects of colistin in critically ill patients

@inproceedings{Spapen2011RenalAN,
  title={Renal and neurological side effects of colistin in critically ill patients},
  author={Herbert D. Spapen and Rita Jacobs and Viola L van Gorp and Joris Troubleyn and Patrick Maurice Honor{\'e}},
  booktitle={Annals of intensive care},
  year={2011}
}
Colistin is a complex polypeptide antibiotic composed mainly of colistin A and B. It was abandoned from clinical use in the 1970s because of significant renal and, to a lesser extent, neurological toxicity. Actually, colistin is increasingly put forward as salvage or even first-line treatment for severe multidrug-resistant, Gram-negative bacterial infections, particularly in the intensive care setting. We reviewed the most recent literature on colistin treatment, focusing on efficacy and… CONTINUE READING
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