Renal and nephron hemodynamics in spontaneously hypertensive rats.

@article{Arendshorst1979RenalAN,
  title={Renal and nephron hemodynamics in spontaneously hypertensive rats.},
  author={William J. Arendshorst and William H. Beierwaltes},
  journal={The American journal of physiology},
  year={1979},
  volume={236 3},
  pages={
          F246-51
        }
}
Renal and nephron hemodynamics were compared between anesthetized, nondiuretic, spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). Although the mean arterial pressure was higher in SHR than in WKY, 158 VS. 114 mmHg, glomerular filtration rate (GFR) and renal blood flow (RBF) were similar in both groups. So were intrarenal hydrostatic pressures, single nephron GFR (SNGFR), and single nephron blood flow (SNBF). Accordingly, the increased renal vascular resistance (RVR) in SHR was… CONTINUE READING

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