Renal and endocrine responses to a renin inhibitor, enalkiren, in normal humans.

@article{Cordero1991RenalAE,
  title={Renal and endocrine responses to a renin inhibitor, enalkiren, in normal humans.},
  author={P Cordero and Naomi D. L. Fisher and T. J. M. Moore and Ray E. Gleason and Gordon H. Williams and Norman Kenneth Hollenberg},
  journal={Hypertension},
  year={1991},
  volume={17 4},
  pages={510-6}
}
Interpretation of renin-angiotensin blockade with angiotensin converting enzyme inhibitors is potentially confounded by their multiple effects. We used a selective renin inhibitor (enalkiren, A-64662) to explore the renal and endocrine effects of angiotensin II in healthy men. Each received 90-minute enalkiren infusions at 2-day intervals, on a low (10 mmol, 16 subjects) and high (200 mmol, 12 subjects) salt diet. Plasma renin activity, immunoreactive plasma angiotensin II and aldosterone… CONTINUE READING
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Inter - nal renin inhibition : Renal hemodynamic and excretory actions of A65317 ( abstract )

  • KM Verburg, GA Young, SH Rosenberg, HD Kleinert
  • ISH
  • 1990

Internal renin inhibition: Renal hemodynamic and excretory actions of A-65317

  • KM Verburg, GA Young, SH Rosenberg, HD Kleinert
  • ISH
  • 1990

Prolonged antihypertensive effect of renin inhibitor treatment (abstract)

  • M Schalekamp, AV Meiracker, F Derkx, AMI Veld, P vanBrummelen
  • Meeting of American Society of Hypertension,
  • 1990
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