Renal and cardiovascular effects of angiotensin-converting enzyme inhibitor plus angiotensin II receptor antagonist therapy in children with proteinuria.

@article{Lubrano2006RenalAC,
  title={Renal and cardiovascular effects of angiotensin-converting enzyme inhibitor plus angiotensin II receptor antagonist therapy in children with proteinuria.},
  author={Riccardo Lubrano and Francesca Soscia and Marco Elli and Flavia Ventriglia and Claudia Raggi and Elisabetta Travasso and Simona Scateni and Valeria di Maio and Paolo Versacci and Raffaele Masciangelo and Stefano Romero},
  journal={Pediatrics},
  year={2006},
  volume={118 3},
  pages={e833-8}
}
OBJECTIVE We investigated whether the combination of an angiotensin-converting enzyme inhibitor and an angiotensin II type 1 receptor antagonist offers better control of proteinuria and cardiovascular parameters without causing adverse side effects. METHODS We enrolled 10 children (mean age: 12.3 +/- 4.06 years) with proteinuria resulting from chronic renal diseases of various causes. The study consisted of 2 phases, 3 months each, for an overall 6-month observation time. During phase 1 (3… CONTINUE READING
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