Renal Effects of Dental Amalgam in Children: The New England Children’s Amalgam Trial

Abstract

BACKGROUND Mercury is nephrotoxic and dental amalgam is a source of mercury exposure. METHODS Children 6-10 years of age (n = 534) with two or more posterior teeth with caries but no prior amalgam restorations, were randomized to one of two treatments--amalgam or resin composite (white fillings)--used for caries treatment during 5 years of follow-up. The… (More)
DOI: 10.1289/ehp.10504

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