Remyelination in the CNS of the hypothyroid rat.

@article{Franklin1996RemyelinationIT,
  title={Remyelination in the CNS of the hypothyroid rat.},
  author={Robin J. M. Franklin and Jennifer M. Gilson},
  journal={Neuroreport},
  year={1996},
  volume={7 9},
  pages={
          1526-30
        }
}
A number of studies have provided good evidence to indicate a role for thyroid hormone in myelination. Since myelination and remyelination have many shared objectives, and may therefore involve similar mechanisms, we examined whether thyroid hormone may also have a role in remyelination by both Schwann cells and oligodendrocytes of spinal cord axons that had been demyelinated by the injection of ethidium bromide in thyroidectomized rats. Neither the extent of oligodendrocyte remyelination nor… CONTINUE READING
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