Removal of the epithelium potentiates acetylcholine in depolarizing canine bronchial smooth muscle.

@article{Gao1988RemovalOT,
  title={Removal of the epithelium potentiates acetylcholine in depolarizing canine bronchial smooth muscle.},
  author={Yong Sheng Gao and Paul Michel Vanhoutte},
  journal={Journal of applied physiology},
  year={1988},
  volume={65 6},
  pages={2400-5}
}
Experiments were designed to determine whether the airway epithelium affects the membrane potential of the underlying smooth muscle. The effect of epithelium removal (by gentle rubbing) on the responsiveness of isolated canine bronchi was studied. Simultaneous recordings of mechanical and electrical activity were made in paired circumferential strips (with… CONTINUE READING