Removal of the 2.2.2 cryptand (Kryptofix 2.2.2) from 18FDG by cation exchange.

@article{Alexoff1991RemovalOT,
  title={Removal of the 2.2.2 cryptand (Kryptofix 2.2.2) from 18FDG by cation exchange.},
  author={D. Alexoff and J. Fowler and S. Gatley},
  journal={International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes},
  year={1991},
  volume={42 12},
  pages={
          1189-93
        }
}
  • D. Alexoff, J. Fowler, S. Gatley
  • Published 1991
  • Chemistry, Medicine
  • International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes
  • The 2.2.2 cryptand [4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo-(8.8.8)-hexacosane] was trapped efficiently on Dowex AG50W-X8 (100-200 mesh) cation exchange resin. The concentration of the 2.2.2 cryptand in water with 0.1-2% methanol, or in 1 N HCl, was decreased by a factor of > 4000 using 1 mL (1.7 mequiv.) of AG50W-X8 and a flow rate of approx. 2 mL/min. K+, Cs+, Ag+ and Ba2+ forms were about equal in their ability to remove the 2.2.2 cryptand. A disposable cartridge containing 1 mL of… CONTINUE READING
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