Removal of cell-bound lipoproteins: a crucial step for the efficient infection of liver cells with hepatitis C virus in vitro.

@article{Favre2001RemovalOC,
  title={Removal of cell-bound lipoproteins: a crucial step for the efficient infection of liver cells with hepatitis C virus in vitro.},
  author={Daniel Favre and Pascale Berthillon and Christian Tr{\'e}po},
  journal={Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie},
  year={2001},
  volume={324 12},
  pages={1141-8}
}
Hepatitis C virus (HCV) is of major social, medical and economic importance. The prevalence of HCV is approximatively 1% in most developed countries, and much higher in developing countries. HCV infection is the second major cause, after hepatitis B virus infection, for the generation of chronic liver disease and hepatocellular carcinoma. To date, the only reliable model for the study of HCV infection is the chimpanzee. Indeed, there is no robust in vitro infection system, yet. There is thus an… CONTINUE READING
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