Remote in vivo imaging of human skin corneocytes by means of an optical fiber bundle.

@article{Dromard2007RemoteIV,
  title={Remote in vivo imaging of human skin corneocytes by means of an optical fiber bundle.},
  author={Tanguy Dromard and Val{\'e}rie Ravaine and Serge Ravaine and J Leveque and Neso Sojic},
  journal={The Review of scientific instruments},
  year={2007},
  volume={78 5},
  pages={053709}
}
Human corneocytes forming the outermost layer of the epidermis (stratum corneum) were imaged in vivo by epifluorescence through a coherent optical fiber bundle. A very simple and rapid method to remotely visualize the cells forming this protective layer of the skin is presented. After the topical application of fluorescein, the distal face of an optical fiber bundle is gently applied perpendicularly onto the labeled skin (contact mode). Remote fluorescence images of the corneocytes are acquired… CONTINUE READING