Remodeling of cerebral arterioles in chronic hypertension.

  title={Remodeling of cerebral arterioles in chronic hypertension.},
  author={Gary L. Baumbach and Donald D. Heistad},
  volume={13 6 Pt 2},
Chronic hypertension impairs dilatation of cerebral arterioles. Impairment of dilatation generally has been attributed to hypertrophy of the vessel wall with encroachment on the vascular lumen. In this study, we tested the hypothesis that a reduction in external diameter may contribute to encroachment on the vascular lumen during chronic hypertension. We examined 10-12-month-old, anesthetized Wistar-Kyoto (WKY) rats and stroke-prone spontaneously hypertensive rats (SHRSP). External diameter… CONTINUE READING