Remodeling of cell-cell and cell-extracellular matrix interactions at the border zone of rat myocardial infarcts.

@article{Matsushita1999RemodelingOC,
  title={Remodeling of cell-cell and cell-extracellular matrix interactions at the border zone of rat myocardial infarcts.},
  author={Tetsuro Matsushita and Masahito Oyamada and Kayoko Fujimoto and Yuko Yasuda and Satoko Masuda and Yuko Wada and Takafumi Oka and Tetsuro Takamatsu},
  journal={Circulation research},
  year={1999},
  volume={85 11},
  pages={1046-55}
}
At the border zone of myocardial infarcts, surviving cardiomyocytes achieve drastic remodeling of cell-cell and cell-extracellular matrix interactions. Spatiotemporal changes in these interactions are likely related to each other and possibly have significant impact on cardiac function. To elucidate the changes, we conducted experimental infarction in rats and performed 3-dimensional analysis of the localization of gap junctions (connexin43), desmosomes (desmoplakin), adherens junctions… CONTINUE READING