Remitting seronegative symmetrical synovitis with pitting edema. RS3PE syndrome.

@article{Mccarty1985RemittingSS,
  title={Remitting seronegative symmetrical synovitis with pitting edema. RS3PE syndrome.},
  author={Daniel J Mccarty and J D O'duffy and Loretta H. Pearson and James I B Hunter},
  journal={JAMA},
  year={1985},
  volume={254 19},
  pages={2763-7}
}
Eight elderly men and two elderly women presented with symmetrical polysynovitis of acute onset involving most of their appendicular joints and flexor digitorum tendons associated with pitting edema of the dorsum of both hands and both feet. Onset of seven of the ten cases could be pinpointed almost to the hour. Rheumatoid factors were absent from serum samples in all, and no radiologically evident erosions developed. Clinical and laboratory signs of inflammation and the edema disappeared… CONTINUE READING

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