5 Citations
Heme oxygenase in neuroprotection: from mechanisms to therapeutic implications
- BiologyReviews in the neurosciences
- 2014
Heme oxygenase was regarded as an enzyme to degrade heme in aging red blood cells; recent studies suggested HO might have other functions such as neuroprotection and up-regulation of HO-1 was also found in brain glial cells in the aging and neurodegenerative diseases.
Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications
- BiologyPharmacological Reviews
- 2005
Understanding of the cellular and molecular mechanisms that regulate the production and mediate the physiological actions of CO has greatly advanced and many diseases, including neurodegenerations, hypertension, heart failure, and inflammation, have been linked to the abnormality in CO metabolism and function.
Different Faces of the Heme-Heme Oxygenase System in Inflammation
- BiologyPharmacological Reviews
- 2003
Pre-induction of HO activity has been demonstrated to ameliorate inflammation and mediate potent resistance to oxidative injury and a better understanding of the complex heme-heme.
Congenital erythropoietic porphyria. I. Case report, special studies and therapy.
- MedicineThe American journal of medicine
- 1968