Remifentanil protects liver against ischemia/reperfusion injury through activation of anti-apoptotic pathways.

@article{Zhao2013RemifentanilPL,
  title={Remifentanil protects liver against ischemia/reperfusion injury through activation of anti-apoptotic pathways.},
  author={G G Zhao and Xin Shen and Haiyan Nan and Linfeng Yan and Haikang Zhao and Jun Yu and Yi Lv},
  journal={The Journal of surgical research},
  year={2013},
  volume={183 2},
  pages={827-34}
}
BACKGROUND Remifentanil protects against ischemia/reperfusion (I/R)-induced organ injury, although its underlying mechanism remains elusive. This study was designed to examine the protective effect of remifentanil preconditioning, if any, against hepatic I/R injury in rats and the underlying mechanism involved. MATERIALS AND METHODS Adult Sprague-Dawley rats were randomly divided into sham operation (S group), ischemia/reperfusion (I/R group), and remifentanil preconditioning (R group) groups… CONTINUE READING

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