• Corpus ID: 8921696

Remarks on the energy costs of insulators in enzymatic cascades

  title={Remarks on the energy costs of insulators in enzymatic cascades},
  author={John P. Barton and Eduardo Sontag},
  journal={arXiv: Molecular Networks},
The connection between optimal biological function and energy use, measuredfor example by the rate of metabolite consumption, is a current topic of interestin the systems biology literature which has been explored in several di erentcontexts. In [1], we related the metabolic cost of enzymatic futile cycles withtheir capacity to act as insulators which facilitate modular interconnections inbiochemical networks. There we analyzed a simple model system in which a signalmolecule regulates the… 
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