Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell.


The polyamines (PAs) spermidine, spermine, putrescine and cadaverine are an essential class of metabolites found throughout all kingdoms of life. In this comprehensive review, we discuss their metabolism, their various intracellular functions and their unusual and conserved regulatory features. These include the regulation of translation via upstream open… (More)
DOI: 10.1016/j.jmb.2015.06.020