Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo.

@article{Ghiretti2014Rem2IA,
  title={Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo.},
  author={Amy E. Ghiretti and Anna R Moore and Rebecca G Brenner and Liang-fu Chen and Anne E West and Nelson C Lau and Stephen D Van Hooser and Suzanne Paradis},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2014},
  volume={34 2},
  pages={
          392-407
        }
}
A key feature of the CNS is structural plasticity, the ability of neurons to alter their morphology and connectivity in response to sensory experience and other changes in the environment. How this structural plasticity is achieved at the molecular level is not well understood. We provide evidence that changes in sensory experience simultaneously trigger multiple signaling pathways that either promote or restrict growth of the dendritic arbor; structural plasticity is achieved through a balance… CONTINUE READING
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