Relocation of the Chromosomal Passenger Complex Prevents Mitotic Checkpoint Engagement at Anaphase


The mitotic checkpoint monitors the attachment of kinetochores to microtubules and delays anaphase onset until all sister kinetochores have become attached to opposite poles [1, 2]. Correct bipolar attachment leads to kinetochore deformation and tension and satisfies the checkpoint [3-6]. What prevents mitotic checkpoint reactivation when sister centromeres… (More)
DOI: 10.1016/j.cub.2010.06.036


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