Reliever-Triggered Inhaled Glucocorticoid in Black and Latinx Adults with Asthma.

  title={Reliever-Triggered Inhaled Glucocorticoid in Black and Latinx Adults with Asthma.},
  author={Elliot Israel and Juan Carlos Cardet and Jennifer Carroll and Anne L. Fuhlbrigge and Lilin She and Frank W. Rockhold and Nancy E. Maher and Maureen Fagan and Victoria E. Forth and Barbara P. Yawn and Paulina Arias Hernandez and Jean Kruse and Brian K. Manning and Jacqueline Rodriguez-Louis and Joel B. Shields and Brianna Ericson and Alex D Colon-Moya and Suzanne Madison and Tamera Coyne-Beasley and Gretchen M Hammer and Barbara M. Kaplan and Cynthia S. Rand and Janet Robles and Opal Thompson and Michael E. Wechsler and Juan P Wisnivesky and Marc D. McKee and Sunit P. Jariwala and Elina Jerschow and Paula J Busse and David C. Kaelber and Sylvette Nazario and Michelle Hernandez and Andrea J. Apter and Ku-Lang Chang and Victor Pinto-Plata and Paul M. Stranges and Laura P. Hurley and Jennifer L. Trevor and Thomas B. Casale and Geoffrey Chupp and Isaretta L. Riley and Kartik V Shenoy and Magdalena Pasarica and Rafael A. Calderon-Candelario and Hazel Tapp and Ahmet Baydur and Wilson D. Pace},
  journal={The New England journal of medicine},
BACKGROUND Black and Latinx patients bear a disproportionate burden of asthma. Efforts to reduce the disproportionate morbidity have been mostly unsuccessful, and guideline recommendations have not been based on studies in these populations. METHODS In this pragmatic, open-label trial, we randomly assigned Black and Latinx adults with moderate-to-severe asthma to use a patient-activated, reliever-triggered inhaled glucocorticoid strategy (beclomethasone dipropionate, 80 μg) plus usual care… 

Albuterol-Budesonide Fixed-Dose Combination Rescue Inhaler for Asthma.

The risk of severe asthma exacerbation was significantly lower with as-needed use of a fixed-dose combination of 180 μg of albuterol and 160 μg of budesonide than with as the needed use of al buterol alone among patients with uncontrolled moderate-to-severe asthma who were receiving a wide range of inhaled glucocorticoid-containing maintenance therapies.

Advances in Evaluation and Treatment of Severe Asthma (Part One).

  • C. Fanta
  • Medicine
    The Medical clinics of North America
  • 2022

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