Relief of menstrual symptoms and migraine with a single-tablet formulation of sumatriptan and naproxen sodium.

BACKGROUND Dysmenorrhea and menstrual migraine may share a common pathogenic pathway. Both appear to be mediated, in part, by an excess of prostaglandin production that occurs during menstruation. METHODS Data were pooled from two replicate randomized controlled trials of 621 adult menstrual migraineurs with dysmenorrhea who treated migraine with… (More)