Relics from the RNA World

  title={Relics from the RNA World},
  author={Daniel C Jeffares and Anthony M. Poole and D. Penny},
  journal={Journal of Molecular Evolution},
An RNA world is widely accepted as a probable stage in the early evolution of life. Two implications are that proteins have gradually replaced RNA as the main biological catalysts and that RNA has not taken on any major de novo catalytic function after the evolution of protein synthesis, that is, there is an essentially irreversible series of steps RNA → RNP → protein. This transition, as expected from a consideration of catalytic perfection, is essentially complete for reactions when the… CONTINUE READING

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