Reliable screening and classification of phosphodiesterase type 5 inhibitors in dietary supplements using gas chromatography / mass spectrometry combined with specific common ions.

@article{Lee2020ReliableSA,
  title={Reliable screening and classification of phosphodiesterase type 5 inhibitors in dietary supplements using gas chromatography / mass spectrometry combined with specific common ions.},
  author={Wonwoong Lee and Hyun Kab Kim and Myung Eun Lee and Beom Hee Kim and Seongchul Park and J. H. Lee and Yongmoon Lee and H. B. Oh and Jongki Hong},
  journal={Journal of chromatography. A},
  year={2020},
  volume={1623},
  pages={
          461210
        }
}
  • Wonwoong Lee, Hyun Kab Kim, +6 authors Jongki Hong
  • Published 2020
  • Chemistry, Medicine
  • Journal of chromatography. A
  • Illegal dietary supplements adulterated with phosphodiesterase type 5 inhibitors (PDE-5i) are increasingly widely distributed through internet markets and underground routes. For this reason, it demands development of reliable screening methods to determine a wide range of PDE-5i drugs in various types of dietary supplements. Herein, we developed a screening method using gas chromatography-mass spectrometry (GC-MS) for simultaneous detection of 53 PDE-5i drugs in supplements. Common… CONTINUE READING

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