Reliable coding emerges from coactivation of climbing fibers in microbands of cerebellar Purkinje neurons.

@article{Ozden2009ReliableCE,
  title={Reliable coding emerges from coactivation of climbing fibers in microbands of cerebellar Purkinje neurons.},
  author={Ilker Ozden and Megan R. Sullivan and Houcheng Lee and Samuel S-H Wang},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2009},
  volume={29 34},
  pages={10463-73}
}
The inferior olive projects climbing fiber axons to cerebellar Purkinje neurons, where they trigger calcium-based dendritic spikes. These responses dynamically shape the immediate spike output of Purkinje cells as well as provide an instructive signal to guide long-term plasticity. Climbing fibers typically fire approximately once a second, and the instructive role is distributed over many such firing events. However, transmission of salient information on an immediate basis needs to occur on a… CONTINUE READING
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