Reliable and efficient scale to assess upper motor neuron disease burden in amyotrophic lateral sclerosis

@article{Quinn2019ReliableAE,
  title={Reliable and efficient scale to assess upper motor neuron disease burden in amyotrophic lateral sclerosis},
  author={Colin Quinn and Christyn Edmundson and Nabila Dahodwala and Lauren Elman},
  journal={Muscle \& Nerve},
  year={2019},
  volume={61},
  pages={508 - 511}
}
Validation of biomarkers of upper motor neuron (UMN) impairment in amyotrophic lateral sclerosis (ALS) requires a reliable clinical assessment of UMN findings. The Penn Upper Motor Neuron Score© (PUMNS) is a standardized measure of UMN signs in ALS. Our aims were to evaluate its intra‐ and inter‐rater reliability, and to examine inter‐item reliability as a proxy for item relatedness and scale efficiency. 
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Reliable and efficient scale to assess upper motor neuron disease burden in amyotrophic lateral sclerosis
  • Presented at: Northeast ALS Consortium Meeting
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