Reliability of two-dimensional and three-dimensional pseudo-continuous arterial spin labeling perfusion MRI in elderly populations: comparison with 15O-water positron emission tomography.

@article{Kilroy2014ReliabilityOT,
  title={Reliability of two-dimensional and three-dimensional pseudo-continuous arterial spin labeling perfusion MRI in elderly populations: comparison with 15O-water positron emission tomography.},
  author={Emily Kilroy and Liana G. Apostolova and Collin Y. Liu and Lirong Yan and John M. Ringman and Danny J. J. Wang},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2014},
  volume={39 4},
  pages={931-9}
}
PURPOSE To investigate the reliability and accuracy of two pseudo-continuous arterial spin labeling (pCASL) sequences, using two-dimensional (2D) gradient-echo echo planar imaging (EPI) and 3D gradient and spin echo (GRASE) as the readout, respectively. MATERIALS AND METHODS Each sequence was performed twice 4 weeks apart on six normal control subjects, six elderly subjects with mild cognitive impairment (MCI), and one participant with Alzheimer's disease (AD). Eight of these subjects also… CONTINUE READING