Reliability of gene expression ratios for cDNA microarrays in multiconditional experiments with a reference design.

Abstract

In a typical gene expression profiling experiment with multiple conditions, a common reference sample is used for co-hybridization with the samples to yield expression ratios. Differential expression for any other sample pair can then be calculated by assembling the ratios from their hybridizations with the reference. In this study we test the validity of… (More)

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