Reliability of concentrations of organophosphate pesticide metabolites in serial urine specimens from pregnancy in the Generation R Study

@article{Spaan2015ReliabilityOC,
  title={Reliability of concentrations of organophosphate pesticide metabolites in serial urine specimens from pregnancy in the Generation R Study},
  author={Suzanne Spaan and Anjoeka Pronk and Holger M Koch and Todd A. Jusko and Vincent W. V. Jaddoe and Pamela A. Shaw and Henning Tiemeier and Albert Hofman and Frank H. Pierik and Matthew Paul Longnecker},
  journal={Journal of Exposure Science and Environmental Epidemiology},
  year={2015},
  volume={25},
  pages={286-294}
}
The widespread use of organophosphate (OP) pesticides has resulted in ubiquitous exposure in humans, primarily through their diet. Exposure to OP pesticides may have adverse health effects, including neurobehavioral deficits in children. The optimal design of new studies requires data on the reliability of urinary measures of exposure. In the present study, urinary concentrations of six dialkyl phosphate (DAP) metabolites, the main urinary metabolites of OP pesticides, were determined in 120… CONTINUE READING

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