Reliability and minimal detectable change of physical performance measures in individuals with pre-manifest and manifest Huntington disease.

@article{Quinn2013ReliabilityAM,
  title={Reliability and minimal detectable change of physical performance measures in individuals with pre-manifest and manifest Huntington disease.},
  author={Lori Quinn and Hanan Khalil and Helen N Dawes and Nora E. Fritz and Deborah A. Kegelmeyer and Anne D. Kloos and Jonathan Gillard and Monica Busse},
  journal={Physical therapy},
  year={2013},
  volume={93 7},
  pages={942-56}
}
BACKGROUND Clinical intervention trials in people with Huntington disease (HD) have been limited by a lack of reliable and appropriate outcome measures. OBJECTIVE The purpose of this study was to determine the reliability and minimal detectable change (MDC) of various outcome measures that are potentially suitable for evaluating physical functioning in individuals with HD. DESIGN This was a multicenter, prospective, observational study. METHODS Participants with pre-manifest and manifest… CONTINUE READING