Relevance of vancomycin-intermediate susceptibility and heteroresistance in methicillin-resistant Staphylococcus aureus bacteraemia.

@article{Khatib2011RelevanceOV,
  title={Relevance of vancomycin-intermediate susceptibility and heteroresistance in methicillin-resistant Staphylococcus aureus bacteraemia.},
  author={Riad Khatib and Jinson Jose and Adina C Musta and Mamta Sharma and Mohamad G Fakih and Leonard B Johnson and Kathleen M Riederer and Stephen P Shemes},
  journal={The Journal of antimicrobial chemotherapy},
  year={2011},
  volume={66 7},
  pages={1594-9}
}
OBJECTIVES To assess the relevance of vancomycin-intermediate susceptibility (VISA) and heteroresistance (hVISA) in methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia. METHODS We determined vancomycin MICs for 371 saved MRSA blood isolates (2002-03; 2005-06) by Etest and broth microdilution (BMD), screened for hVISA (Etest methods), determined the population analysis profile (PAP)/AUC for isolates with suspected reduced susceptibility (MICs >2 mg/L and/or hVISA-screen-positive… CONTINUE READING
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Characterization of vancomycin heteroresistant Staphylococcus aureus (hVISA) from the Detroit Metropolitan area over a 22-year period (1986-2007)

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