Relevance of spontaneous activity to urinary bladder function: an in vitro and in vivo study.

@article{Levin1986RelevanceOS,
  title={Relevance of spontaneous activity to urinary bladder function: an in vitro and in vivo study.},
  author={Robert M. Levin and Michael R Ruggieri and Sujala Velagapudi and David Gordon and Boris Altman and Alan J. Wein},
  journal={The Journal of urology},
  year={1986},
  volume={136 2},
  pages={517-21}
}
The presence and functional significance (if any) of spontaneous activity in the normal urinary bladder during filling is a controversial subject. One model used by many investigators to study spontaneous activity has been isolated urinary bladder smooth muscle strips. Although spontaneous activity is a property commonly observed in isolated urinary bladder strip preparations, the in vitro whole bladder preparation (rabbit) is devoid of spontaneous activity. Additionally, under normal… CONTINUE READING

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