Relevance of positive patch-test reactions to cocamidopropyl betaine and amidoamine.

@article{Brey2004RelevanceOP,
  title={Relevance of positive patch-test reactions to cocamidopropyl betaine and amidoamine.},
  author={Nicole L Brey and Joseph F. Fowler},
  journal={Dermatitis : contact, atopic, occupational, drug},
  year={2004},
  volume={15 1},
  pages={7-9}
}
BACKGROUND Cocamidopropyl betaine (CAPB) is a surfactant, primarily used in personal cleansing products, that may cause allergic contact dermatitis (ACD). Amidoamine (AA), a by-product and a known contaminant in CAPB synthesis, may be the true allergen responsible for some cases of CAPB allergy. Co-reactivity with these allergens and cocamide diethanolamine (CDEA) and formaldehyde has been noted anecdotally. OBJECTIVE This study investigated (1) the correlation and clinical relevance of… CONTINUE READING