Relevance of nuclear receptor expression in a Tchreg cell line, HOZOT: RXRα and PPARγ negatively regulate IFN-γ production.

Abstract

Nuclear receptors (NRs) have recently received much attention for their newly discovered roles in T cell development, as exemplified by RARα (Treg cells) and RORγt (Th17 cells). In previous studies, we characterized a new type of T cell subset, designated as Tchreg (cytotoxic, helper, and regulatory T) cells, in terms of its cytokine signature. In this… (More)
DOI: 10.1016/j.rinim.2012.08.001

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Cite this paper

@article{Suzuki2012RelevanceON, title={Relevance of nuclear receptor expression in a Tchreg cell line, HOZOT: RXRα and PPARγ negatively regulate IFN-γ production.}, author={Motoyuki Suzuki and Makoto Takeuchi and Kazue Tsuji-Takayama and Akira Harashima and Takeshi Otani and Terumasa Toraya and Hiroki Kakuta and Fumiyuki Yamasaki and Shuji Nakamura and Masayoshi Kibata}, journal={Results in immunology}, year={2012}, volume={2}, pages={158-65} }