Relevance of internal time and circadian robustness for cancer patients

Abstract

Adequate circadian timing of cancer treatment schedules (chronotherapy) can enhance tolerance and efficacy several-fold in experimental and clinical situations. However, the optimal timing varies according to sex, genetic background and lifestyle. Here, we compute the individual phase of the Circadian Timing System to decipher the internal timing of each… (More)
DOI: 10.1186/s12885-016-2319-9

7 Figures and Tables

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