Relevance of hypointense lesions on fast fluid-attenuated inversion recovery MR images as a marker of disease severity in cases of multiple sclerosis.

@article{Rovaris1999RelevanceOH,
  title={Relevance of hypointense lesions on fast fluid-attenuated inversion recovery MR images as a marker of disease severity in cases of multiple sclerosis.},
  author={Marco Rovaris and Giancarlo Comi and M A Rocca and Mara Cercignani and Bruno Colombo and Giuseppe Santuccio and Massimo Filippi},
  journal={AJNR. American journal of neuroradiology},
  year={1999},
  volume={20 5},
  pages={813-20}
}
BACKGROUND AND PURPOSE Hypointense lesions can be visible on fast fluid-attenuated inversion recovery (FLAIR) MR images of the brain of patients with multiple sclerosis (MS), and they may be produced by severely damaged white matter. To test the role of these lesions as an MR marker of MS severity, we assessed their relationship with clinical findings and other MR measures. METHODS Using a 1.5-T scanner, dual-echo rapid acquisition with relaxation enhancement, fast FLAIR, and T1-weighted MR… CONTINUE READING