Relevance of extracellular matrix and its receptors in mammalian nephrogenesis revealed by metanephric organ culture system.

Abstract

Mammalian nephrogenesis is modulated by a number of extracellular matrix (ECM) glycoproteins, integrins and cell adhesion molecules. We demonstrated the existence of integrins alphavbeta1, alphavbeta3, alphavbeta5 and alphavbeta6 in epithelial elements of developing nephrons. Fibrillin-1 is a putative ligand for integrin alphavbeta3, and tubulointerstitial… (More)

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@article{Wada2002RelevanceOE, title={Relevance of extracellular matrix and its receptors in mammalian nephrogenesis revealed by metanephric organ culture system.}, author={Jun Wada and Yashpal S. Kanwar and Hirofumi Makino}, journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association}, year={2002}, volume={17 Suppl 9}, pages={75-7} }