Release the hounds! A chemokine elicits monocytes from bone marrow

Abstract

Figure 1 Nef exits infected cells, enters B cells and suppresses CSR. Nef provides communication between infected and bystander cells by an unknown mechanism. Myristylated (‘m’ in orange circles) membrane-associated Nef then signals in B cells to increase expression of IκBα, SOCS1 and SOCS3. In turn, these block the release of transcription factor NF-κB and… (More)
DOI: 10.1038/ni0306-230

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