Release profiles and morphological characterization by atomic force microscopy and photon correlation spectroscopy of 99mTechnetium-fluconazole nanocapsules.

@article{Assis2008ReleasePA,
  title={Release profiles and morphological characterization by atomic force microscopy and photon correlation spectroscopy of 99mTechnetium-fluconazole nanocapsules.},
  author={Danielle Nogueira de Assis and Vanessa Carla Furtado Mosqueira and Jos{\'e} M{\'a}rio Carneiro Vilela and Margareth Spangler Andrade and Valbert Nascimento Cardoso},
  journal={International journal of pharmaceutics},
  year={2008},
  volume={349 1-2},
  pages={152-60}
}
Several classes of antifungal have been employed in candidiasis treatment, but patients with advanced immunodeficiency can present unsatisfactory results after therapy. In these cases, high doses of drugs or the use of multiple agents are sometimes used, and hence increasing the risk of serious side effects. Considering theses difficulties, the encapsulation of antifungal agents in nanoparticulate carriers has been used with the objective of modifying the pharmacokinetic of drugs resulting in… CONTINUE READING