Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia.

@article{Florquin2001ReleaseOU,
  title={Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia.},
  author={Sandrine Florquin and Jos{\'e} G van den Berg and Dariusz Piotr Olszyna and Nike Claessen and Steven M. Opal and Jan J. Weening and Tom van der Poll},
  journal={Kidney international},
  year={2001},
  volume={59 6},
  pages={2054-61}
}
BACKGROUND The urokinase receptor (uPAR; CD87) is a multifunctional molecule involved in fibrinolysis, in proteolysis, in renal tubular functions, and in migration and adhesion of inflammatory cells to the site of infection. METHODS To gain insight into systemic and local release of uPAR and into its regulation during urosepsis, which is one of the leading causes of chronic renal failure, uPAR was measured in urine and plasma of healthy human controls (N = 20), patients with culture-proven… CONTINUE READING

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