Release of the vascular permeability factor in minimal change nephrotic syndrome is related to CD4+ lymphocytes.

@article{Tomizawa1990ReleaseOT,
  title={Release of the vascular permeability factor in minimal change nephrotic syndrome is related to CD4+ lymphocytes.},
  author={Shuichi Tomizawa and Nobuyuki Nagasawa and Koutatsu Maruyama and Naoya Shimabukuro and Hidenori Arai and Takayoshi Kuroume},
  journal={Nephron},
  year={1990},
  volume={56 3},
  pages={
          341-2
        }
}
Shigeru Tomizawa, MD, Department of Pediatrics, Gunma University School of Medicine, Maebashi, Gunma (Japan) Dear Sir, The production of the vascular permeability factor (VPF) from peripheral blood T lymphocytes in nephrotic patients has been confirmed by both Heslan et al. [1] and ourselves [2]. Furthermore, the appearance of significant proteinuria and reduction of anionic sites in the glomeru-lar basement membrane of rat kidneys after infusion of the supernatant of T lymphocyte cultures from… CONTINUE READING

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