Release of the Ca(2+) oscillation-inducing sperm factor during mouse fertilization.

@article{Knott2003ReleaseOT,
  title={Release of the Ca(2+) oscillation-inducing sperm factor during mouse fertilization.},
  author={Jason Glenn Knott and Manabu Kurokawa and Rafael A. Fissore},
  journal={Developmental biology},
  year={2003},
  volume={260 2},
  pages={536-47}
}
A cytosolic sperm protein(s), referred to as the sperm factor (SF), is thought to induce intracellular calcium ([Ca(2+)](i)) oscillations during fertilization in mammalian eggs. These oscillations, which are responsible for inducing complete egg activation, persist for several hours. Nevertheless, whether a protracted release of SF is responsible for the duration of the oscillations is unknown. Using a combination of intracytoplasmic sperm injection (ICSI), in vitro fertilization (IVF), sperm… CONTINUE READING
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