Release of superoxide anion by alveolar macrophages in pulmonary sarcoidosis.

@article{Aerts1986ReleaseOS,
  title={Release of superoxide anion by alveolar macrophages in pulmonary sarcoidosis.},
  author={Chris Bakker Rien Aerts and Benoit Wallaert and Jean Marie Grosbois and Claire Voisin},
  journal={Annals of the New York Academy of Sciences},
  year={1986},
  volume={465},
  pages={193-200}
}
Biological mechanisms involving nonprotease factors mediate the alterations of the alveolar structures which lead to the interstitial fibrosis of pulmonary sarcoidosis. Thus, we have investigated the production of oxidant species by BAL cells from 50 sarcoidosis patients and 18 healthy controls using a lucigenin-dependent CL method. Spontaneous and PMA-induced CL's were significantly higher in untreated patients and treated patients than in spontaneously cured patients or healthy controls (p… CONTINUE READING

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