Release of rifampicin from chitosan, PLGA and chitosan-coated PLGA microparticles.

Abstract

Recently three groups of rifampicin (RIF)-loaded microparticles (MPs), consisting of chitosan (CHT), PLGA and PLGA/CHT mixtures, were assessed in terms of RIF-loading and retention during nebulisation. The CHT-coated PLGA MPs were found to exhibit high RIF-loading ability together with nebulisation ability, stability, and mucoadhesive properties. All MP… (More)
DOI: 10.1016/j.colsurfb.2008.08.010

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