Release of pyrazolone derivatives from suppositories formulated with hydrophilic and hydrophobic bases.

@article{Beirevi1986ReleaseOP,
  title={Release of pyrazolone derivatives from suppositories formulated with hydrophilic and hydrophobic bases.},
  author={M Be{\'c}irevi{\'c} and V Petrici{\'c}},
  journal={Die Pharmazie},
  year={1986},
  volume={41 5},
  pages={338-40}
}
The release and dissolution of aminophenazone and propyphenazone from suppositories prepared with Witepsol (H 15 and S 55), Suppocire (BM and AS 2), and macrogols 400 and 4000 placed in a small volume of water enclosed within a semipermeable wall, were followed by measuring the concentrations of dissolved drug that crossed the wall into an outside aqueous… CONTINUE READING