Release of metabolic enzymes by Giardia in response to interaction with intestinal epithelial cells.

@article{Ringqvist2008ReleaseOM,
  title={Release of metabolic enzymes by Giardia in response to interaction with intestinal epithelial cells.},
  author={Emma Ringqvist and J. E. Daniel Palm and Hanna Skarin and Adrian B Hehl and Malin Weiland and Barbara J. Davids and David S. Reiner and William J Griffiths and Lars Eckmann and Frances D. Gillin and Staffan G. Sv{\"a}rd},
  journal={Molecular and biochemical parasitology},
  year={2008},
  volume={159 2},
  pages={85-91}
}
Giardia lamblia, an important cause of diarrheal disease, resides in the small intestinal lumen in close apposition to epithelial cells. Since the disease mechanisms underlying giardiasis are poorly understood, elucidating the specific interactions of the parasite with the host epithelium is likely to provide clues to understanding the pathogenesis. Here we tested the hypothesis that contact of Giardia lamblia with intestinal epithelial cells might lead to release of specific proteins. Using… CONTINUE READING

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