Release of interleukin-1 beta associated with potent cytocidal action of staphylococcal alpha-toxin on human monocytes.

@article{Bhakdi1989ReleaseOI,
  title={Release of interleukin-1 beta associated with potent cytocidal action of staphylococcal alpha-toxin on human monocytes.},
  author={Sucharit Bhakdi and M Muhly and Stephan Korom and Ferdinand Hugo},
  journal={Infection and immunity},
  year={1989},
  volume={57 11},
  pages={3512-9}
}
The pathogenetic relevance of Staphylococcus aureus alpha-toxin in humans has been debated because human cells have been thought to display a natural resistance toward the cytotoxic action of this cytolysin. Following our previous demonstration that human platelets represent sensitive targets for toxin attack, we have now identified monocytes as a second… CONTINUE READING