Release of endothelial cell lipoprotein lipase by plasma lipoproteins and free fatty acids.

@article{Saxena1989ReleaseOE,
  title={Release of endothelial cell lipoprotein lipase by plasma lipoproteins and free fatty acids.},
  author={Umesh Saxena and L D Witte and Ira J Goldberg},
  journal={The Journal of biological chemistry},
  year={1989},
  volume={264 8},
  pages={4349-55}
}
Lipoprotein lipase (LPL) bound to the lumenal surface of vascular endothelial cells is responsible for the hydrolysis of triglycerides in plasma lipoproteins. Studies were performed to investigate whether human plasma lipoproteins and/or free fatty acids would release LPL which was bound to endothelial cells. Purified bovine milk LPL was incubated with cultured porcine aortic endothelial cells resulting in the association of enzyme activity with the cells. When the cells were then incubated… CONTINUE READING