Release of creatine kinase and prostaglandin E2 from regenerating skeletal muscle fibers.

@article{McArdle1994ReleaseOC,
  title={Release of creatine kinase and prostaglandin E2 from regenerating skeletal muscle fibers.},
  author={Anne McArdle and R. Timothy Edwards and Malcolm J. Jackson},
  journal={Journal of applied physiology},
  year={1994},
  volume={76 3},
  pages={1274-8}
}
To study the effect of regeneration on the release of creatine kinase (CK) and prostaglandin E2 from muscle, extensor digitorum longus muscles of mice were injected with 50 microliters of BaCl2 solution in saline (1.2% wt/vol). Injected muscles showed almost complete degeneration at 3 days postinjection but had regenerated to approximately the same fiber cross-sectional area as contralateral control muscles by 12 days postinjection. These muscles released reduced amounts of intracellular CK… CONTINUE READING

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