Release of cholecystokinin in the central nervous system.

  title={Release of cholecystokinin in the central nervous system.},
  author={Maurizio Raiteri and Paolo Paudice and Francesco Vallebuona},
  journal={Neurochemistry international},
  volume={22 6},
The octapeptide cholecystokinin (CCK) is one of the most abundant neuropeptides of the central nervous system. A number of features (for instance heterogeneity of the regional distribution, subcellular localization at the nerve terminal level, calcium-dependent release upon nervous tissue depolarization) support the candidacy of CCK as a neurotransmitter. The reported co-existence of CCK and dopamine in some meso-limbic neurons has led to speculation that the neuropeptide may interact with the… CONTINUE READING