Release of an Endogenous Pyrogen in Vitro from Rabbit Mononuclear Cells

@article{Atkins1967ReleaseOA,
  title={Release of an Endogenous Pyrogen in Vitro from Rabbit Mononuclear Cells},
  author={Elisha Atkins and Phyllis T. Bodel and Lorraine Francis},
  journal={The Journal of Experimental Medicine},
  year={1967},
  volume={126},
  pages={357 - 384}
}
The capacity of rabbit mononuclear cells to release an endogenous pyrogen (EP) in vitro has been studied. After incubation with tuberculin, preparations of predominantly monocytic cells, derived from the respiratory passages of the lungs of rabbits sensitized with BCG, were activated to release EP. Pyrogen production occurred more slowly with lung monocytes… CONTINUE READING